Single Molecule Photonics - AFM-TIRF / SNOM

Contact: Dr. Volker Walhorn

    Research Topic: Single molecules can nowadays be investigated by means of optical, mechanical and electrical methods. Single molecule fluorescence imaging and spectroscopy yield valuable and quantitative information about optical properties, spatial distribution and temporal dynamics of single molecules.
We have developped 1) scanning near-field optical microscopy (SNOM) for single molecule imaging and spectroscopy and 2) a small-cantilever based AFM combined with total internal reflection fluorescence (TIRF) microscopy for ultrasensitive LIF detection of individual fluorophores and simultaneous AFM control and manipulation at the molecular level.
    Images: (a) Aperture-less SNOM setup and single dye molecule imaged at 20 nm optical resolution. (b) combined AFM-TIRF with imaging and control of single semiconductor nanocrystal.
    References: ... see section Publications

Last updated: 07.02.2017