Header
 

Nanopores - SINGLE MOLECULE TRANSLOCATION

Contact: Prof. Dr. Dario Anselmetti

     
    Research Topic: The translocation dynamics of individual macromolecules like DNA or DNA-protein complexes (EcoRI, RecA, peroxiredoxines) through solid-state nanopores (SiNx, graphene, MoS2, BN, ...) is quantitativly investigated by optical tweezers force control. Beyond looking into the physical mechanisms involved we explore the possibility of future sequencing and diagnostic applications thereof.
     
   
    Images: Solid-state Si3N4 nanopore with a diameter of 30 nm (left). Experimental concept of DNA-translocation with optical tweezers manipulation (middle). Experimental results from single protein (EcoRI) translocation (right).
     
    References: ... see section Publications

Last updated: 07.02.2017