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Micro- & Nanofluidics - MIGRATION & DYNAMICS OF BIOMOLECULES

Contact: Dr. Martina Viefhues

     
    Research Topic: In this research project we investigate and develop novel micro- and nanofluidical chip device applications that can be used for separation, sorting and harvesting of macromolecules and colloids. We use structured micro- and nanofluidic environments and drive the molecular objects far from thermoddynamic equilibrium to explore non-linear migration mechanisms like absolute negative mobility, dielectrophoretic trapping, molecular ratcheting or chiral separation.
In addition, we design and develop lab-on-a-chip devices where individual cells like E. coli can be trapped and analyzed according their active metabolism by UV-laser-induced fluorescence.
     
   
    Images: Structured microchip platform (left), separation of macromolecules and complexes with microchip based nanoslit dielectrophoresis (middle left), baseline separation of plasmid mixture with on-chip dielectrophoresis (middle right), absolute negative mobility of colloidal particles (right).
     
    References: ... see section Publications

Last updated: 07.02.2017