SFB 613: Physik von Einzelmolekülprozessen und molekularer Erkennung in organischen Systemen

Workshop on

"Recognition and adsorption processes of biomolecules"

Universität Bielefeld
Fakultät für Physik

6-7 March, 2006

Room D2-136





Aim and scope

Biological systems such as the immune system rely on the ability of biomolecules to specifically recognise each other. The investigation of recognition and adsorption processes of biomolecules has gained growing interest in different scientific disciplines such as biology, biochemistry, physics and computer sciences. The workshop focuses on recent developments in experimental, computational and theoretical approaches to molecular recognition and thus tries to bridge between the different scientific disciplines. Bringing together scientists from different fields in an informal and casual way hopefully encourages discussions leading to a positive and fruitful impact on future research activities. An exchange of different scientific methods to approach the problem of molecular recognition should eventually enable a better understanding of the underlying basic mechanisms.

Organisers

Hans Behringer (Universität Bielefeld)
Andreas Degenhard (Universität Bielefeld)
Friederike Schmid (Universität Bielefeld)

E-mail: adegenha@physik.uni-bielefeld.de (issues concerning organisation)

E-mail: hans.behringer@physik.uni-bielefeld.de (issues concering scientific program)

List of contributors

Michael Bachmann, Universität Leipzig, Germany
Hans Behringer, Universität Bielefeld, Germany
Karsten Goede, Universität Leipzig, Germany
Joël Janin, Université Paris-Sud, France
Doron Lancet, Weizmann Institute of Science, Israel
Alexey Polotsky, Sérvice de Physique de l'Etat Condensé CEA/Saclay, France
Robert Ros, Universität Bielefeld, Germany
Vakhtang Rostiashvili, Max-Planck-Institut für Polymerforschung, Mainz, Germany
Rebecca Wade, European Molecular Biology Laboratory and EML Research, Heidelberg, Germany
Martin Zacharias, International University Bremen, Germany


Program

Monday, 6 March

9:20 Opening
9:30-10:15 A. Polotsky
Correlated Random Copolymer Adsorption
10:30-11:15 V. Rostiashvili
Globular Structure of Helix - Coil Copolymers: A Self - Consistent - Field Treatment
11:30-12:15 J. Janin
Statistical Physics of protein-protein recognition
12:30-13:30 Lunch break
13:30-14:15 M. Zacharias
Protein-Protein and Protein-Ligand Docking Accounting for Local and Global Flexibility
14:30-15:15 H. Behringer
A Simple Spin Model for Investigating Molecular Recognition
15:30-16:15 R. Wade
Computational Approaches to Biomolecular Recognition
16:30-17:30 Discussion forum
19:00 Dinner

Tuesday, 7 March

9:30-10:15 R. Ros
Single Molecule Recognition: From Transcriptional Regulation to Supramolecular Chemistry
10:30-11:15 D. Lancet
Molecular recognition in biological repertoires
11:30-12:15 M. Bachman
Complex Conformational-Phase Diagrams of Simple Hybrid Polymer-Substrate Models
12:30-13:30 Lunch break
13:30-14:15 K. Goede
Experiments on Specific Adhesion and Clustering of Peptides on Semiconductor Surfaces