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Label-free Detection of Proteins
in Gels via UV-LIF - PROTEOMIC TOOLS
Contact: Dr. Katja Tönsing |
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Based on our optical detection technology,
we filed a (world-wide) patent for the ultrasensitive and label-free
detection of proteins in 1D/2D-PAGE gels by UV-LIF together
with our industrial partner SOLVIAS (Basel). The new technology
allows fast, efficient and sensitive (1 ng) protein detection
in gels with a label- and staining-free protocol with a mass
dynamic of 4 orders of magnitude. |
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Images: UV-LIF setup, ultrasensitive and label-free
protein detection in 2D acrylamide gel |
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Project 1 |
Testing of UV-LIF Detection Technology
With Proteomic Applications |
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We currently explore the limits and possibilities
of this fascinating technology with interested partners in the
field of proteomics. |
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Publications: [see section "Publications"] |
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Collaborations: M. Blüggel, Protagen,
Dortmund; P. Berndt, H. Langen, Hoffmann-La Roche, Basel, J.
Kalinowski, Dept. of Genetics, Bielefeld University. |
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other ongoing projects [...] |
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