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Optical Tweezers - SINGLE
MOLECULE BIOSENSOR & MANIPULATION
Contact: Prof. Dr. Dario Anselmetti |
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Research Topic: Micron-sized objects like beads, colloids
or cells can be trapped, steered and manipulated by light and
allow force experiments at the single molecule level with a force sensitivity
level of 0.1 pN. We set up two high stability single-beam optical
tweezers (OT) system on an inverted light microscope which allows
analytical force spectroscopy, adhesion and elasticity experiments with single molecules
or cells in an experimental force range of 0.1-900 pN. |
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Images: OT scheme (left), single-molecule elasticity biosensor for measuring DNA binding agents (middle),
and single cell adhesion experiments with a functionalized polystyrene bead (right). |
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References: ... see section Publications |
Last updated: 06.02.2017
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