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Research Topic: The translocation dynamics of individual macromolecules
like DNA or DNA-protein complexes (EcoRI, RecA, peroxiredoxines) through solid-state nanopores (SiNx, graphene, MoS2, BN, ...) is quantitativly
investigated by optical tweezers force control. Beyond looking into
the physical mechanisms involved we explore the possibility
of future sequencing and diagnostic applications thereof. |