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Magnetic Tweezers - SINGLE
MOLECULE MANIPULATION WITH MAGNETIC FIELDS
Contact: Prof. Dr. Dario Anselmetti / Dr. A. Sischka |
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Magnetic microbeads can be trapped, manipulated
and torsionally steered by external magnetic fields and allow
force experiments at the single molecule level at a sensitivity
level of below 0.1 pN. A new magnetic tweezers (MT) apparatus
(PicoTwist, Lyon - France) allows quantitative and analytical
experiments with single molecules |
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Images: MT measurement scheme (left), MT apparatus
(middle), force response of a torsionally constrained dsDNA
molecule on external torque forces ("hat curve"). |
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Project 1 |
Monitoring DNA recognition and
enzymatic reactions at the single molecule level |
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Description: coming soon ... |
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Publications: [see section "Publications"] |
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Collaborations: T. Glaser,
Anorganic Chemistry, Faculty of Chemistry, Bielefeld University |
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Project 2 |
Molecular motors at work |
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Description: coming soon ... |
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Publications: [see section "Publications"] |
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Collaborations: K.-J. Dietz,
Plant Physiology, Faculty of Biology, Bielefeld University |
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